Nutrigenomics (also known as nutritional genomics) is broadly defined as the relationship between nutrients, nutrition, and gene expression. Okay, so what about nutriepigenetics? Well, that’s a portmanteau of nutritional epigenetics, a field of science that operates at the molecular level. Nutrition epidemists are specifically studying the interaction between molecules in food and molecules that bind to DNA to control gene expression. Therefore, dietary methyl groups, DNA methylation, and the resulting gene expression are
the field of nutritional epidemiologists.
Nutrigenomics involves the characterization of gene products, their physiological function and their interactions. It focuses on the effect of nutrients on the genome, proteome, and metabolome (fig., and explains the relationship between these specific nutrients and nutrient regimes on human health. Nutrigenomics is studying how nutrients interact with our genes to improve our health
influence.
This new science provides new insights into how we can use nutrition to prevent and treat diseases. Nutrigenomics is the science of how your food communicates with your genes. It looks at how what we eat can turn on or off specific parts of our genes, which helps us avoid or treat illnesses. Nutrigenomics brings new terminology, novel experimental techniques, and a fundamentally new approach to nutrition research, such as high-throughput technologies that enable the global study of gene expression in
a cell or an organism.
Part of the approach is nutrigenomics, which is about finding markers for the early phase of diet-related diseases; that is the phase in which diet-related interventions can make the patient healthy again (Ramesha et al. Although it is tempting to focus on single-nutrient effects, such as the folate example mentioned above, nutrigenomics researchers believe that the real focus should be on the effects of multiple nutrient imbalances (both in excess and in deficiency) on the genome. Determining the optimal concentration of micronutrients required to keep cells in a genomically stable state remains one of the biggest challenges for nutrigenomics researchers. Much of nutrigenomic research was on single
nucleotide polymorphisms (SNPs)), DNA sequence variations, which account for 90% of all genetic variations in humans.
They used nutritionally efficient silkworm strains as markers, assisted selection or gene transfer in silkworm breeding programs, and found that this developed molecular analysis could be used in silkworms for the benefit of farmers in the silkworm industry. In nutrigenomics studies, they also emphasized the future prospects of the functional mechanism of silkworms. Nutrigenomics makes it clear that every person is unique and can react differently to the same food due to their individual genetic makeup. An important goal of nutrigenomics research is to investigate genome-wide dietary influences. A particular focus is on the role of metabolic stress in the development of metabolic syndrome, the collection of phenotypes that combine inflammation, metabolic stress, insulin resistance and diabetes. It covers a general overview of nutrigenomics, associated diseases, and the role of SNP in gene alterations, dietary supplements,
and sensitization of public.
As a result, nutritional research shifted from epidemiology and physiology to molecular biology and genetics, and nutrigenomics was born. These studies show how nutrigenomics can refine diets and improve health outcomes for various people. Therefore, there must be a general awareness of nutrition and diet-related problems that lead to gene alterations. For this reason, nutrigenomics should be investigated in detail (Fig. Nutrigenomics can lead to personalized diets that are tailored to individual genetic
profiles and thus a promote optimal health.