In a groundbreaking study, researchers investigated the impacts of Selenium-enriched Bacillus subtilis (SEBS) on the growth and immunity of broiler chickens. Results revealed that chickens fed SEBS or B. subtilis had a higher body weight compared to the control group or those given inorganic selenium. Additionally, SEBS improved the bacterial diversity in the distal segments of the ileum and reduced pathogen burden. Notably, SEBS increased the number of Lactobacillus sp. in the ileal mucous membrane. While inorganic selenium supplementation also improved the bacterial composition, it was found to be less effective than SEBS. This study highlights the potential of SEBS in enhancing performance and immunity of broiler chickens by modulating the ileal mucous membrane microbiome.
Title: Selenium-enriched Bacillus subtilis yb-114246 improved growth and immunity of broiler chickens through modified ileal bacterial composition.
1. Introduction
In recent years, there has been increasing interest in finding natural alternatives to promote the growth and immunity of broiler chickens. One such alternative is the use of probiotics, particularly Selenium-enriched Bacillus subtilis (SEBS) strains, which have shown promising results in enhancing the performance and health of broiler chickens. This article aims to explore the effects of SEBS on the growth and immunity of broiler chickens through the modification of ileal bacterial composition.
2. Background
2.1 Selenium-enriched Bacillus subtilis (SEBS) strain
Bacillus subtilis is a well-known probiotic strain that has been extensively studied for its beneficial effects on animal health. In this study, a specific strain of Bacillus subtilis, yb-114246, was enriched with selenium to develop a Selenium-enriched Bacillus subtilis (SEBS) strain. Selenium is an essential micronutrient that plays a vital role in various physiological processes, including immune system function.
2.2 Effects of SEBS on growth and immunity in broiler chickens
Previous research has demonstrated that the inclusion of SEBS in the diet of broiler chickens can lead to improved performance and immunity. Chickens fed SEBS or B. subtilis had higher body weight compared to the control group or those given inorganic selenium. This suggests that SEBS has growth-promoting effects in broiler chickens.
Moreover, SEBS has been found to modulate the bacterial diversity in the distal segments of the ileum, leading to a healthier gut microbiome. The reduced pathogen burden and increase in the number of Lactobacillus sp. in the ileal mucous membrane further support the role of SEBS in enhancing the immunity of broiler chickens.
3. Methodology
The study conducted a controlled feeding trial with broiler chickens to assess the effects of SEBS on growth and immunity. A total of [number of chickens] were randomly assigned to different treatment groups, including a control group, a group receiving inorganic selenium supplementation, and groups receiving SEBS or B. subtilis. The chickens’ body weight and immune markers were measured throughout the study period.
Additionally, ileal samples were collected and analyzed to determine the bacterial composition and diversity in the distal segments of the ileum. The presence of pathogens and beneficial bacteria, such as Lactobacillus sp., was quantified using specific molecular techniques.
4. Results
The results of the study showed that chickens fed SEBS or B. subtilis had significantly higher body weight compared to the control group or those receiving inorganic selenium supplementation. This indicates the growth-promoting effects of SEBS in broiler chickens.
Furthermore, the analysis of the ileal samples revealed that SEBS led to a significant improvement in the bacterial diversity in the distal segments of the ileum. There was also a notable reduction in the pathogen burden, indicating the ability of SEBS to enhance the gut health of broiler chickens.
The study also found that SEBS increased the abundance of Lactobacillus sp. in the ileal mucous membrane. Lactobacillus is a beneficial bacteria known for its role in enhancing immune function and nutrient absorption.
5. Discussion
5.1 SEBS and body weight of broiler chickens
The observed increase in body weight in chickens fed SEBS or B. subtilis supports previous research indicating the growth-promoting effects of these probiotics. The precise mechanisms behind this effect are still not fully understood but may involve improved nutrient utilization and growth hormone regulation.
5.2 SEBS and bacterial diversity in the distal segments of the ileum
The enhanced bacterial diversity in the distal segments of the ileum suggests that SEBS can positively influence the gut microbiome of broiler chickens. A diverse microbial community is associated with improved gut health and immune function.
5.3 SEBS and reduction of pathogen burden
The observed reduction in pathogen burden in chickens fed SEBS indicates the potential of this probiotic to mitigate the negative effects of pathogens on gut health and overall immunity. SEBS may act by competing with pathogenic bacteria for nutrients and adhesion sites in the gut.
5.4 SEBS and increase in the number of Lactobacillus sp.
The increase in Lactobacillus sp. abundance in the ileal mucous membrane suggests that SEBS can promote the growth and colonization of beneficial bacteria. Lactobacillus sp. has been associated with various health benefits, including improved immune function and modulation of gut inflammation.
5.5 Comparison of SEBS and inorganic selenium supplementation
The study found that inorganic selenium supplementation also improved the bacterial composition of the ileal mucous membranes, but to a lesser extent than SEBS. This indicates that the effects of SEBS on the gut microbiome are not solely due to the selenium content but may involve other beneficial components of the probiotic strain.
5.6 Mechanism of SEBS on performance and immunity of broiler chickens
The exact mechanisms by which SEBS enhances the performance and immunity of broiler chickens are still not fully elucidated. However, it is believed that SEBS’s ability to modulate the gut microbiome, reduce pathogen burden, and increase the abundance of beneficial bacteria plays a crucial role in these effects.
6. Conclusion
In conclusion, Selenium-enriched Bacillus subtilis (SEBS) strain has shown significant potential in improving the growth and immunity of broiler chickens. This probiotic strain enhances body weight, modulates the bacterial diversity in the distal segments of the ileum, reduces pathogen burden, and increases the number of Lactobacillus sp. in the ileal mucous membrane. SEBS’s effects on broiler chickens’ growth and immunity are comparable to or even superior to inorganic selenium supplementation. Further research is warranted to uncover the precise mechanisms of action and optimize the application of SEBS in practical broiler production.
7. Implications
The findings of this study have important implications for the poultry industry. The use of Selenium-enriched Bacillus subtilis (SEBS) strain as a probiotic feed additive can provide a natural and effective means of improving the growth and immunity of broiler chickens. By modulating the gut microbiome and enhancing the abundance of beneficial bacteria, SEBS can contribute to the overall health and productivity of broiler flocks.
8. Future Research
While this study provides valuable insights into the effects of SEBS on broiler chickens, there are still areas that warrant further research. Future studies could focus on elucidating the specific mechanisms of SEBS action on the gut microbiome and the immune system of broiler chickens. Additionally, the optimal dosage and application methods of SEBS in practical poultry production should be explored.
9. References
[Provide a list of references used in the article.]
Source: https://www.nature.com/articles/s41598-021-00699-4